Empreses del Grup Pere Mata

Grup de Genètica i Ambient en les Psicosis (GAP)

	MEMBRES
	Vilella Cuadrada, Elisabet (Investigadora responsable) Abasolo Zabalo, Nerea Albacar Sancho, Gloria Alonso Pérez, Yolanda De Pablo Rabassó, Joan Franco Vásquez, José Gabriel Gaviria Gómez, Ana Milena Martorell Bonet, Lourdes Mena Sánchez, Isaias Miralles Ibiza, Carme Moreno Samaniego, Lorena Rosich Estragó, Marcel Sáez Navarro, Cristina Torrell Galcerán, Helena Valero Oyarzábal, Joaquín Valiente Pallejà, Alba

PROJECTES

Títol: Mutaciones en el ADN mitocondrial que contribuyen en el autismo y a las características propias de las enfermedades mitocondriales presentes en pacientes con trastorno del espectro autista.
Investigador principal: Lourdes Martorell Bonet.
Investigadors col·laboradors: Yolanda Alonso, Helena Torrell, Francisco Aguilera.
Entitat finançadora: Fondo de Investigación Sanitaria. Instituto de Salud Carlos III.

Període d'execució: 2012-2015.

Títol: Alteraciones de la melina en función del genotipo DDRI en pacientes esquizofrénicos: estudios clínico y molecular.
Investigador principal: Elisabet Vilella Cuadrada.
Investigadors col·laboradors: Adela Masana, Gloria Albacar, Joaquín Timoneda, Joaquín Valero, Nerea Abasolo, Fernando López, Silvia Acosta, Helena Boixadera, Francesc Xavier Ramon, Ester Salvadó, Jordi Muntané.
Entitat finançadora: Fondo de Investigación Sanitaria. Instituto de Salud Carlos III.

Període d'execució: 2012-2015.

PUBLICACIONS

ANY 2014

Stojanovic A, Martorell L, Montalvo I, Ortega L, Monseny R, Vilella E, Labad J. Increased serum interleukin-6 levels in early stages of psychosis: associations with at-risk mental states and the severity of psychotic symptoms. Psychoneuroendocrinology. 2014 Mar;41:23-32. doi: 10.1016/j.psyneuen.2013.12.005. Epub 2013 Dec 14. IF: 5,591. 1r quartil.

Miralles C, Alonso Y, Verge B, Setó S, Gaviria AM, Moreno L, Cortés MJ, Gutiérrez-Zotes A, Vilella E, Martorell L. Personality dimensions of schizophrenia patients compared to control subjects by gender and the relationship with illness severity. BMC Psychiatry. 2014 May 24;14(1):151. doi: 10.1186/1471-244X-14-151. IF: 2,237. 2n quartil.

Montalvo I, Gutiérrez-Zotes A, Creus M, Monseny R, Ortega L, Franch J, Lawrie SM, Reynolds RM, Vilella E, Labad J. Increased prolactin levels are associated with impaired processing speed in subjects with early psychosis. PLoS One. 2014 Feb 24;9(2):e89428. doi: 10.1371/journal.pone.0089428. eCollection 2014. IF: 3,534. 1r quartil.

Manzanares N, Monseny R, Ortega L, Montalvo I, Franch J, Gutiérrez-Zotes A, Reynolds RM, Walker BR, Vilella E, Labad J. Unhealthy lifestyle in early psychoses: the role of life stress and the hypothalamic-pituitary-adrenal axis. Psychoneuroendocrinology. 2014 Jan;39:1-10. doi: 10.1016/j.psyneuen.2013.09.023. Epub 2013 Oct 1. IF: 5,591. 1r quartil.

Franco JG, de Pablo J, Gaviria AM, Sepúlveda E, Vilella E. Smooth pursuit eye movements and schizophrenia: Literature review. Arch Soc Esp Oftalmol. 2014 Sep;89(9):361-7. doi: 10.1016/j.oftal.2014.02.007. Epub 2014 Jun 19.

Torrell H, Salas A, Abasolo N, Morén C, Garrabou G, Valero J, Alonso Y, Vilella E, Costas J, Martorell L. Mitochondrial DNA (mtDNA) variants in the European haplogroups HV, JT, and U do not have a major role in schizophrenia. Am J Med Genet B Neuropsychiatr Genet. 2014 Oct;165(7):607-17. doi: 10.1002/ajmg.b.32264. Epub 2014 Aug 17. IF: 3,271. 2n quartil.

Abasolo N, Roig B, Martorell L, Martínez-Leal R, Aguilera F, Camacho-García RJ, Orejuela C, Scholl FG, Martinez-Mir A, Vilella E. Genetic study of NRXN1β variants in Spanish patients with schizophrenia. Schizophr Res. 2014 Nov;159(2-3):554-5. doi: 10.1016/j.schres.2014.09.002. Epub 2014 Sep 18. IF: 4,426. 1r quartil.

Gabriel Franco J, Santesteban O, Trzepacz P, Bernal C, Valencia C, Ocampo MV, Pablo Jd, Gaviria AM, Vilella E. MMSE items that predict incident delirium and hypoactive subtype in older medical inpatients. Psychiatry Res. 2014 Dec 30;220(3):975-81. doi: 10.1016/j.psychres.2014.09.003. Epub 2014 Sep 16. IF: 2,682. 2n quartil.

Lopez-Seco F, Masana-Marin A, Vilella E. [Importance of screening attention deficit hyperactivity disorder in adults]. Rev Neurol. 2014 Dec 1;59(11):526-7. Spanish. IF: 0,926. 4rt quartil.

Labad J, Stojanovic-Pérez A, Montalvo I, Solé M, Cabezas A, Ortega L, Moreno I, Vilella E, Martorell L, Reynolds RM, Gutiérrez-Zotes A. Stress biomarkers as predictors of transition to psychosis in at-risk mental states: Roles for cortisol, prolactin and albumin. J Psychiatr Res. 2015 Jan;60:163-9. doi: 10.1016/j.jpsychires.2014.10.011. Epub 2014 Nov 11. IF: 4,092. 1r quartil.

ANY 2013

Toma C, Hervás A, Balmaña N, Salgado M, Maristany M, Vilella E, Aguilera F, Orejuela C, Cuscó I, Gallastegui F, Pérez-Jurado LA, Caballero-Andaluz R, Diego-Otero YD, Guzmán-Alvarez G, Ramos-Quiroga JA, Ribasés M, Bayés M, Cormand B. Neurotransmitter systems and neurotrophic factors in autism: association study of 37 genes suggests involvement of DDC. World J Biol Psychiatry. 2013 Sep;14(7):516-27. IF: 3,571. 2n quartil.

Torrell H, Montaña E, Abasolo N, Roig B, Gaviria AM, Vilella E, Martorell L. Mitochondrial DNA (mtDNA) in brain samples from patients with major psychiatric disorders: gene expression profiles, mtDNA content and presence of the mtDNA common deletion. Am J Med Genet B Neuropsychiatr Genet. 2013 Mar;162B(2):213-23. IF: 3,231. 2n quartil.

Montalvo I, Ortega L, López X, Solé M, Monseny R, Franch J, Vilella E, Labad J. Changes in prolactin levels and sexual function in young psychotic patients after switching from long-acting injectable risperidone to paliperidone palmitate. Int Clin Psychopharmacol. 2013 Jan;28(1):46-9. IF: 2,705. 2n quartil.

Toma C, Hervás A, Torrico B, Balmaña N, Salgado M, Maristany M, Vilella E, Martínez-Leal R, Planelles MI, Cuscó I, Del Campo M, Pérez-Jurado LA, Caballero-Andaluz R, de Diego-Otero Y, Pérez-Costillas L, Ramos-Quiroga JA, Ribasés M, Bayés M, Cormand B. Analysis of two language-related genes in autism: a case-control association study of FOXP2 and CNTNAP2. Psychiatr Genet. 2013 Apr;23(2):82-5. FI: 2,581. 2n quartil.

Gutiérrez-Zotes JA, Farnós A, Vilella E, Labad J. Higher psychoticism as a predictor of thoughts of harming one's infant in postpartum women: A prospective study. Compr Psychiatry. 2013 Oct;54(7):1124-9. IF: 2,376. 2n quartil.

Toma C, Hervás A, Torrico B, Balmaña N, Salgado M, Maristany M, Vilella E, Martínez-Leal R, Planelles MI, Cuscó I, del Campo M, Pérez-Jurado LA, Caballero-Andaluz R, de Diego-Otero Y, Pérez-Costillas L, Ramos-Quiroga JA, Ribasés M, Bayés M, Cormand B. Analysis of two language-related genes in autism: a case-control association study of FOXP2 and CNTNAP2. Psychiatr Genet. 2013 Apr;23(2):82-5. IF: 2,365. 3r quartil.

Franco JG, Trzepacz PT, Meagher DJ, Kean J, Lee Y, Kim JL, Kishi Y, Furlanetto LM, Negreiros D, Huang MC, Chen CH, Leonard M, de Pablo J. Three Core Domains of Delirium Validated Using Exploratory and Confirmatory Factor Analyses. Psychosomatics. 2013 May-Jun;54(3):227-38. FI: 2,123. 2n quartil.

Franco JG, Trzepacz PT, Meagher DJ, Kean J, Lee Y, Kim JL, Kishi Y, Furlanetto LM, Negreiros D, Huang MC, Chen CH, Leonard M, de Pablo J. Three core domains of delirium validated using exploratory and confirmatory factor analyses. Psychosomatics. 2013 May-Jun;54(3):227-38. IF: 1,732. 2n quartil.

Hernandez A, Gallardo-Pujol D, Pereda N, Arntz A, Bernstein DP, Gaviria AM, Labad A, Valero J, Gutiérrez-Zotes JA. Initial Validation of the Spanish Childhood Trauma Questionnaire-Short Form: Factor Structure, Reliability and Association With Parenting. J Interpers Violence. 2013 May;28(7):1498-518. FI: 1,639. 1r quartil.

Hernandez A, Gallardo-Pujol D, Pereda N, Arntz A, Bernstein DP, Gaviria AM, Labad A, Valero J, Gutiérrez-Zotes JA. Initial Validation of the Spanish Childhood Trauma Questionnaire-Short Form: Factor Structure, Reliability and Association With Parenting. J Interpers Violence. 2013 May;28(7):1498-518. IF: 1,355. 1r quartil.

Hernández Sarmiento JM, Correa N, Correa M, Franco JG, Alvarez M, Ramírez C, Gómez LM, Toro AC, Londoño NH, Martínez M, Restrepo MA, Zapata E, Mejía GI, Robledo J. Tuberculosis among homeless population from Medellín, Colombia: associated mental disorders and socio-demographic characteristics. J Immigr Minor Health. 2013 Aug;15(4):693-9. IF: 1,007. 3r quartil.

Martinez Velilla N, Franco JG. [Subsyndromal delirium in elderly patients: a systematic review]. Rev Esp Geriatr Gerontol. 2013 May-Jun;48(3):122-9.

Xifró A, Miró F, Setó S, Alonso Y. Urgencias psiquiátricas y luna llena. Emergencias. 2013 ;25:514. IF: 2,578. 1r quartil.

TESIS DOCTORALS

Títol: Anàlisi de l'ADNmt en el trastorn mental greu.
Doctoranda: Helena Torrell
Directors: Lourdes Martorell

Data de lectura: 22/05/2014
Universitat: Universitat Rovira i Virgili

Títol: Relación de la esquizotípia con el perfil de personalidad patológica y el rendimiento cognitivo en hermanos de pacientes con psicosis.
Doctoranda: Lorena Moreno
Directors: Ana Gaviria i Antonio Labad

Data de lectura: 31/10/2014
Universitat: Universitat Rovira i Virgili

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